Endocrine Abstracts

Diabetes mellitus (DM) is a metabolic disease, which is accompanied by systemic damage to organs, including the central nervous system. Clinically, these changes are associated with cognitive impairment, the pathogenesis of which is also largely heterogeneous.Objective: To evaluate the role of tau-protein in the diagnosis of cognitive impairment in patients with type 1 and type 2 diabetes.Materials and methods: The study was tested...

Purpose of the studyEvaluation of cerebral microcirculation using contrast and non-contrast magnetic resonance perfusion in patients with type 1 diabetes and cognitive dysfunction.Material and methodsThe study complied with generally accepted ethical rules. The study included 45 patients with type 1 diabetes mellitus with cognitive dysfunction and 20 patients without. All patients were continuously monitored ...

Actuality: Currently, there is no doubt about the negative effect of diabetes mellitus (DM) on the state of the central nervous system. One of the pathological manifestations are anatomical changes in the brain, which in turn can lead to the development of functional disorders and cognitive decline. Conducting imaging research methods allows us to assess the presence or absence of brain atrophy at an early stage.The aim: To identify the relationship betw...

The goal was to study neuroplasticity in patients with diabetes mellitus using neuroimaging techniques. We examined 80 patients with diabetes mellitus type 1 and 2. All were conducted general clinical examination, neuropsychological testing - MoCa test, test 12 words. All patients underwent continuous glycemic monitoring and HbA1c assessment. An MRI study was also performed on Siemens 1.5 T, the protocol included a standard examination of the brain, a proton spectroscopy, and ...

Objective: To determine the effect of glycemic variability on cognitive function in patients with type 1 diabetes mellitus.Materials: Thirty patients with type 1 diabetes mellitus were examined at the age of 29.7 (27.45–30.4) years, the duration of the disease was 19 (15.1–20.3) years. Patients were divided into 2 groups: 1st group (n=15) – patients with cognitive impairment, 2nd group (n=15) – without.<p class="...

Introduction: Visceral obesity is a primary risk factor for metabolic syndrome and is associated with short- and long-term effects on physical and psychosocial health. It is now known that body mass index (BMI), which is used as the main method of diagnosing obesity, does not allow the assessment of body composition and differentiation of visceral adipose tissue.The aim of the study. To investigate the features of body composition that influence metabolic risks in primary scho...

Objective: To study the peculiarities of the composition in patients over 50 years old.Materials and Methods: The study involved 136 adults aged 50 to 82 years. All subjects underwent complex examination, which included anthropometry (height, weight, body mass index (BMI)) and body composition analysis using Inbody 770 (Inbody Co.Ltd., Korea). Statistical processing of the results was performed using MedCalc Statistic software.Results: women’s age w...

Actuality: At present, the role of chronic hyperglycemia in type 1 diabetes mellitus (DM1) in the onset of diabetic encephalopathy has been proven. At the same time, violations in the metabolic composition of brain cells were detected in persons with DM1, estimated with the proton magnetic resonance spectroscopy (1H-MRS). However, the relationship between the results of these studies has not yet been studied.The aim: To reveal the relationship...